The effectiveness of an experimental treatment for alcoholism depends on the genetic makeup of the people who receive it, according to a new study. The finding may help doctors personalize treatments for people who abuse alcohol.
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Among people with the LL genotype, those receiving ondansetron had fewer drinks per day than those receiving placebo and over 11% more days without a drink. Ondansetron’s effects among those with the LL variant were even more pronounced when those people also carried the TT gene variant.
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