NIH-Led Scientists Find Antibodies that Prevent Most HIV Strains from Infecting Human Cells Discovery to Advance HIV Vaccine Design, Antibody Therapy for Other Diseases

Scientists have discovered two potent human antibodies that can stop more than 90 percent of known global HIV strains from infecting human cells in the laboratory, and have demonstrated how one of these disease-fighting proteins accomplishes this feat. According to the scientists, these antibodies could be used to design improved HIV vaccines, or could be further developed to prevent or treat HIV infection. Moreover, the method used to find these antibodies could be applied to isolate therapeutic antibodies for other infectious diseases as well.